Two new studies published online this week help shed light on the off-target toxicity of the CETP inhibitor torcetrapib, but the studies conflict regarding the atheroprotective functionality of the HDL cholesterol resulting with the drug.
Heartwire
It tripled the patient's chances for surviving to hospital discharge in a retrospective study; discharge was five times more likely if there was also bystander cardiopulmonary resuscitation.
Heartwire
This study compares machine learning techniques for neuroimaging diagnosis with traditional radiology methods.
Brain
Behavioral factors were main cause of association between depression and adverse cardiac events in patients with coronary heart disease.
Medscape Medical News
Tune in to hear Drs. Silberstein, Saper, and Freitag discuss the progression and treatment of acute migraine, including how to manage migraine attacks associated with cutaneous allodynia.
Medscape Neurology & Neurosurgery
A 60-year-old woman presents with abnormal behavior, irritability, disorientation, forgetfulness, and unsteadiness while walking (including repeated falls). Her symptoms have evolved gradually over the past 3 months. She has also developed intermittent jerking limb movements. An electroencephalogram (EEG) is obtained. What diagnosis is suggested by the EEG?
eMedicine Case Presentations
Results of a randomized trial show that telcagepant, also known as MK-0974, is effective in the treatment of migraine, with efficacy similar to zolmitriptan but with fewer adverse effects.
Medscape Medical News
Randomized trial results show no benefit from the use of insulin-like growth-factor type 1 after 2 years of treatment in patients with amyotrophic lateral sclerosis.
Medscape Medical News
A meta-analysis examining the efficacy of second-generation antipsychotics in the treatment of schizophrenia shows there are small differences, suggesting other factors, including adverse effects and cost, should be considered in treatment choice.
Medscape Medical News
Physical inactivity, smoking, and poor adherence to medication probably explain why people with depression are at higher risk of CV events, and not "fancy physiological mediators," investigators for the Heart and Soul Study say.
Heartwire